hrp0097p1-19 | Bone, Growth Plate and Mineral Metabolism | ESPE2023

Bone mineral density development in children with chronic non-bacterial osteomyelitis treated with zoledronate

Soucek Ondrej , Cebecauerova Dita , Malcova Hana , Sumnik Zdenek

Introduction: Chronic non-bacterial osteomyelitis (CNO) is a sterile inflammatory disease of the skeleton characterized by local pain and swelling. If first line treatment (non-steroidal anti-inflammatory drugs) fails, bisphosphonates are recommended. There are no randomized controlled studies so far that would clarify the zoledronate efficiency, and also no study systematically exploring the effect on bone mineral density (BMD)....